Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11526919 | 0.84 | ALDH1A1 (0.60) | TDP1ALDH1A1TSHRALOX15L3MBTL1 | |
| SCHEMBL11528538 | 0.83 | ALDH1A1 (0.50) | TDP1ALDH1A1TSHRALOX15L3MBTL1 | |
| SCHEMBL22317679 | 0.80 | KMT2A (0.36) | TDP1ALDH1A1TSHRALOX15L3MBTL1 | |
| SCHEMBL11529872 | 0.80 | TDP1 (0.48) | TDP1ALDH1A1TSHRALOX15L3MBTL1 | |
| SCHEMBL10037101 | 0.79 | NQO1 (0.58) | TDP1ALDH1A1TSHRL3MBTL1LMNA | |
| SCHEMBL11526401 | 0.79 | TDP1 (0.46) | TDP1ALDH1A1TSHRALOX15L3MBTL1 | |
| SCHEMBL11531493 | 0.77 | APP (0.45) | TDP1ALDH1A1TSHRALOX15L3MBTL1 | |
| SCHEMBL11528528 | 0.77 | APP (0.45) | TDP1ALDH1A1TSHRALOX15L3MBTL1 | |
| SCHEMBL14424034 | 0.76 | CXCL12 (0.50) | ALDH1A1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL14424036 | 0.76 | NPC1 (0.51) | LMNACYP3A4CYP2D6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161474-A | STABILIZERS, ANTIOZONANTS FOR VULCANIZABLE DIENE RUBBERS | MONSANTO COMPANY (US) | 1979-07-17 | — | — | US | disclosed |