Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 6/20 | 0.40 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | STK3 | Q13188 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11528526 | 0.78 | LTB4R (0.50) | DRD2DRD3MAOBLTB4RLTB4R2 | |
| SCHEMBL761098 | 0.75 | MAP3K14 (0.50) | HCRTR2MAP3K14DRD2DRD3MAOB | |
| SCHEMBL6899244 | 0.70 | HCRTR2 (0.43) | HCRTR2MAP3K14DRD2DRD3CHEK1 | |
| SCHEMBL16519791 | 0.70 | HCRTR2 (0.49) | HCRTR2MAP3K14DRD2DRD3CHEK1 | |
| SCHEMBL12066982 | 0.70 | HCRTR2 (0.52) | HCRTR2 | |
| SCHEMBL24075137 | 0.68 | HCRTR2 (0.50) | HCRTR2DRD2DRD3MAOBCYP19A1 | |
| SCHEMBL761292 | 0.68 | DRD2 (0.44) | HCRTR2DRD2DRD3CYP19A1ADRA2A | |
| SCHEMBL29449962 | 0.68 | DRD2 (0.44) | HCRTR2DRD2DRD3CYP19A1ADRA2A | |
| SCHEMBL24075753 | 0.68 | HCRTR2 (0.50) | HCRTR2DRD2DRD3MAOBCYP19A1 | |
| SCHEMBL18512270 | 0.68 | HCRTR2 (0.50) | HCRTR2DRD2DRD3MAOBCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178380-A | LIPOGENSIS INHIBITORS | SHELL OIL COMPANY (US) | 1979-12-11 | — | — | US | disclosed |
| US-4103021-A | BENZODIOXIN AND BENZOPYRAN CARBOXAMIDES | SHELL OIL COMPANY (US) | 1978-07-25 | — | — | US | disclosed |