Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.50 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527656 | 0.78 | HCRTR2 (0.40) | LTB4RLTB4R2MAOBDRD2DRD3 | |
| SCHEMBL1706738 | 0.76 | LTB4R (0.62) | LTB4RLTB4R2CYP3A4MAOAMAOB | |
| SCHEMBL4524534 | 0.74 | IMPDH2 (0.41) | LTB4RLTB4R2MAOAMAOBLTA4H | |
| SCHEMBL4119538 | 0.73 | LTB4R (0.54) | LTB4RLTB4R2CYP3A4MAOAMAOB | |
| SCHEMBL20182779 | 0.73 | LTB4R (0.54) | LTB4RLTB4R2CYP3A4MAOAMAOB | |
| SCHEMBL30256850 | 0.73 | LTB4R (0.54) | LTB4RLTB4R2CYP3A4MAOAMAOB | |
| SCHEMBL14395468 | 0.73 | LTB4R (0.54) | LTB4RLTB4R2CYP3A4MAOAMAOB | |
| SCHEMBL4119534 | 0.73 | LTB4R (0.54) | LTB4RLTB4R2CYP3A4MAOAMAOB | |
| SCHEMBL4119536 | 0.73 | LTB4R (0.54) | LTB4RLTB4R2CYP3A4MAOAMAOB | |
| Hydrochloric Acid SCHEMBL20179510 | 0.71 | LTB4R (0.53) | LTB4RLTB4R2CYP3A4MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178380-A | LIPOGENSIS INHIBITORS | SHELL OIL COMPANY (US) | 1979-12-11 | — | — | US | disclosed |