Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3687429 | 0.84 | ALDH1A1 (0.67) | KMT2AALDH1A1APPMEN1POLB | |
| SCHEMBL25747602 | 0.83 | POLB (0.64) | KMT2AALDH1A1APPMAOBMEN1 | |
| SCHEMBL11347760 | 0.78 | TSHR (0.64) | ALDH1A1APPMAOBKDM4EGAA | |
| SCHEMBL19335350 | 0.77 | MAOB (0.48) | KMT2AALDH1A1MAOBMEN1KDM4E | |
| SCHEMBL7803228 | 0.76 | IGF1R (0.53) | ALDH1A1APPPOLB | |
| SCHEMBL13736583 | 0.75 | CALM1 (0.64) | ALDH1A1MAOBKDM4EGAASMN1; SMN2 | |
| SCHEMBL2007090 | 0.75 | ALDH1A1 (0.56) | KMT2AALDH1A1MEN1KDM4EHSD17B10 | |
| SCHEMBL30514387 | 0.74 | MAOB (0.70) | KMT2AALDH1A1MAOBMEN1TDP1 | |
| SCHEMBL119396 | 0.74 | MAOB (0.70) | KMT2AALDH1A1MAOBMEN1TDP1 | |
| SCHEMBL6099115 | 0.74 | MAOB (0.53) | KMT2AAPPMAOBMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163759-A | Process for preparing aromatic hydroxyaldehydes | HAARMANN & REIMER GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-08-07 | — | — | US | disclosed |