Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.35 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.31 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27984896 | 0.83 | AR (0.45) | ARMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL27984838 | 0.83 | AR (0.36) | ARMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL28026566 | 0.80 | L3MBTL1 (0.57) | ARL3MBTL1ALDH1A1ALOX15MAPT | |
| SCHEMBL11528761 | 0.76 | ALDH1A1 (0.40) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL29269817 | 0.75 | ICAM1 (0.42) | MEN1KMT2AHCAR2L3MBTL1ALDH1A1 | |
| SCHEMBL3561461 | 0.74 | HCAR2 (0.43) | MEN1KMT2AHCAR2L3MBTL1ALDH1A1 | |
| SCHEMBL29957082 | 0.74 | HCAR2 (0.43) | MEN1KMT2AHCAR2L3MBTL1ALDH1A1 | |
| SCHEMBL28818787 | 0.73 | AGBL2 (0.39) | ARHCAR2ALDH1A1ALOX15MAPT | |
| SCHEMBL38666287 | 0.72 | MEN1 (0.45) | ARMEN1KMT2AHCAR2KDM6B | |
| SCHEMBL8882943 | 0.72 | AR (0.43) | ARMEN1KMT2AHCAR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790166-A | imidazopyridine compounds for the treatment of cancer | 诺华股份有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-104837829-A | Inhibitor compounds | CANCER REC TECH LTD | 2015-08-12 | — | — | CN | disclosed |
| CN-104540834-A | Novel thienopyrimidine derivatives, preparation method and therapeutic use thereof | SANOFI SA | 2015-04-22 | — | — | CN | disclosed |
| CN-104203925-A | 5-aminopyrimidine derivatives and use thereof for combating undesired plant growth | BAYER IP GMBH | 2014-12-10 | — | — | CN | disclosed |
| US-4144339-A | TREATMENT OF BILHARZIASIS | RHONE-POULENC INDUSTRIES (FR) | 1979-03-13 | — | — | US | disclosed |
| US-4138487-A | NEMATOCIDES | RHONE-POULENC INDUSTRIES (FR) | 1979-02-06 | — | — | US | disclosed |
| US-4110450-A | BILHARZIASIS | RHONE-POULENC INDUSTRIES (FR) | 1978-08-29 | — | — | US | disclosed |