Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11530054 | 0.73 | FAAH (0.41) | ALDH1A1TSHRFAAH | |
| SCHEMBL11675774 | 0.72 | — | — | |
| SCHEMBL3267696 | 0.71 | ALDH1A1 (0.34) | ALDH1A1TSHRFAAH | |
| SCHEMBL6888117 | 0.70 | TRPA1 (0.35) | ALDH1A1 | |
| SCHEMBL11528652 | 0.70 | ALDH1A1 (0.41) | ALDH1A1GAAFAAH | |
| SCHEMBL11091749 | 0.69 | MAPT (0.45) | ALDH1A1GAATDP1FAAH | |
| SCHEMBL27580578 | 0.69 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL5132322 | 0.69 | ALDH1A1 (0.39) | ALDH1A1GAAZDHHC20ZDHHC2TSHR | |
| SCHEMBL22168230 | 0.67 | — | — | |
| SCHEMBL9555829 | 0.67 | ALDH1A1 (0.32) | ALDH1A1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156735-A | SALIDIURETICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| US-4118501-A | SALIDIURETIC ACTIVITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |