Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | GFER | P55789 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | CNR2 | P34972 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.50 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11044474 | 0.88 | LMNA (0.68) | LMNAALDH1A1GFERMAPK1RECQL | |
| SCHEMBL11529730 | 0.84 | LMNA (0.44) | LMNAALDH1A1GFERMAPK1RECQL | |
| SCHEMBL11529218 | 0.84 | LMNA (0.64) | LMNAALDH1A1GFERMAPK1RECQL | |
| SCHEMBL9180552 | 0.82 | LMNA (0.52) | LMNAALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL11529878 | 0.81 | LMNA (0.60) | LMNAALDH1A1GFERMAPK1RECQL | |
| SCHEMBL20161350 | 0.81 | HRH4 (0.44) | LMNAALDH1A1GFERMAPK1RECQL | |
| SCHEMBL14036484 | 0.81 | LMNA (0.44) | LMNAALDH1A1GFERMAPK1RECQL | |
| SCHEMBL1038338 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL11532602 | 0.81 | CNR2 (0.56) | LMNAALDH1A1GFERMAPK1RECQL | |
| SCHEMBL11528378 | 0.80 | HRH4 (0.66) | LMNAALDH1A1GFERMAPK1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4157343-A | Preparation of aromatic diamines | UOP INC. (US) | 1979-06-05 | — | — | US | disclosed |