Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.56 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | GFER | P55789 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.47 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11529383 | 0.83 | LOXL2 (0.44) | CNR2PANK3ALDH1A1MAPTLMNA | |
| SCHEMBL1655689 | 0.81 | ALDH1A1 (0.60) | CNR2PANK3ALDH1A1MAPTLMNA | |
| SCHEMBL11044474 | 0.81 | LMNA (0.68) | CNR2PANK3ALDH1A1MAPTLMNA | |
| SCHEMBL11528386 | 0.81 | LMNA (0.58) | CNR2PANK3ALDH1A1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL6759854 | 0.79 | CNR2 (0.53) | CNR2PANK3ALDH1A1MAPTLMNA | |
| SCHEMBL13359832 | 0.79 | LMNA (0.57) | CNR2PANK3ALDH1A1MAPTLMNA | |
| SCHEMBL2504209 | 0.78 | KDM4E (0.68) | MAPTCYP3A4KDM4ELOXL2MMP8 | |
| SCHEMBL1735497 | 0.78 | ALDH1A1 (0.74) | CNR2ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL11529218 | 0.78 | LMNA (0.64) | CNR2PANK3ALDH1A1MAPTLMNA | |
| SCHEMBL3047826 | 0.77 | CNR2 (0.73) | CNR2PANK3ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11168084-B2 | Purine based compounds as toll-like receptor 9 antagonist | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2021-11-09 | — | — | US | disclosed |
| EP-3707140-B1 | PURINE BASED COMPOUNDS AS TOLL-LIKE RECEPTOR 9 ANTAGONISTS | COUNCIL SCIENT IND RES (IN) | 2021-10-13 | — | — | EP | disclosed |
| US-20200347062-A1 | PURINE BASED COMPOUNDS AS TOLL-LIKE RECEPTOR 9 ANTAGONIST | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-11-05 | — | — | US | disclosed |
| US-4157343-A | Preparation of aromatic diamines | UOP INC. (US) | 1979-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11168084-B2 | Purine based compounds as toll-like receptor 9 antagonist | TLR9, TLR1, TLR7 | CNR2 319/4885PANK3 335/4885ALDH1A1 2973/4885 |
| US-20200347062-A1 | PURINE BASED COMPOUNDS AS TOLL-LIKE RECEPTOR 9 ANTAGONIST | TLR9, TLR1, TLR7 | CNR2 321/4885PANK3 365/4885ALDH1A1 2999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.