Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.79 |
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | HPGD | P15428 | 2/20 | 0.79 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.79 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.79 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.79 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.79 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.79 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.79 |
| ▸ | IMPDH2 | P12268 | 17/20 | 0.57 |
| ▸ | IMPDH1 | P20839 | 15/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1151899 | 0.94 | ALDH1A1 (0.81) | ALDH1A1LMNAHPGDABCC4NR1I2 | |
| SCHEMBL9807972 | 0.92 | ALDH1A1 (0.81) | ALDH1A1LMNAHPGDABCC4NR1I2 | |
| SCHEMBL9807970 | 0.92 | ALDH1A1 (0.81) | ALDH1A1LMNAHPGDABCC4NR1I2 | |
| SCHEMBL9807884 | 0.92 | ALDH1A1 (0.84) | ALDH1A1LMNAHPGDABCC4NR1I2 | |
| SCHEMBL9807876 | 0.92 | ALDH1A1 (0.84) | ALDH1A1LMNAHPGDABCC4NR1I2 | |
| SCHEMBL12149641 | 0.92 | ALDH1A1 (0.89) | ALDH1A1LMNAHPGDABCC4NR1I2 | |
| SCHEMBL1152649 | 0.92 | ALDH1A1 (0.78) | ALDH1A1LMNAHPGDABCC4NR1I2 | |
| Hydrochloric Acid SCHEMBL9807986 | 0.92 | ALDH1A1 (0.80) | ALDH1A1LMNAHPGDABCC4NR1I2 | |
| Hydrochloric Acid SCHEMBL9807983 | 0.92 | ALDH1A1 (0.80) | ALDH1A1LMNAHPGDABCC4NR1I2 | |
| Hydrochloric Acid SCHEMBL9807931 | 0.92 | ALDH1A1 (0.82) | ALDH1A1LMNAHPGDABCC4NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028564-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF FILOVIRUS-MEDIATED DISEASES | ZALICUS INC. | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028564-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF FILOVIRUS-MEDIATED DISEASES | FLNA, FLNB, PIGS | ALDH1A1 3453/4885LMNA 156/4885HPGD 2731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.