Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | EZH2 | Q15910 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475763 | 0.77 | ATM (0.45) | RECQLGAAPOLBL3MBTL1ATM | |
| SCHEMBL2033235 | 0.77 | ATM (0.45) | RECQLGAAPOLBL3MBTL1ATM | |
| SCHEMBL77511 | 0.71 | RECQL (0.55) | RECQLGAAPOLBL3MBTL1ATM | |
| SCHEMBL9472885 | 0.70 | RECQL (0.46) | RECQLGAAPOLBL3MBTL1ATM | |
| SCHEMBL29453034 | 0.69 | RECQL (0.53) | RECQLGAAPOLBL3MBTL1ATM | |
| SCHEMBL11528816 | 0.69 | RECQL (0.41) | RECQLGAAPOLBL3MBTL1ATM | |
| SCHEMBL8892298 | 0.69 | GAA (0.54) | RECQLGAAPOLBL3MBTL1ATM | |
| SCHEMBL3295977 | 0.69 | RECQL (0.57) | RECQLGAAPOLBL3MBTL1ATM | |
| SCHEMBL10525290 | 0.69 | RECQL (0.57) | RECQLGAAPOLBL3MBTL1ATM | |
| SCHEMBL13297934 | 0.69 | RECQL (0.88) | RECQLGAAPOLBL3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140673-A | REACTING 4-AMINO-PIPERIDINES WITH ENOLIC ETHERS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |