Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11526195 | 0.84 | NNMT (0.50) | CYP1A2PIN1KMT2AMEN1TSHR | |
| SCHEMBL11529393 | 0.82 | HTR1A (0.37) | CYP1A2PIN1KMT2AMEN1NPC1 | |
| SCHEMBL11528907 | 0.78 | CTDSP1 (0.48) | CYP1A2PIN1KMT2AMEN1NPC1 | |
| SCHEMBL29524945 | 0.78 | CYP1A2 (0.56) | CYP1A2KMT2AMEN1NPC1TSHR | |
| SCHEMBL13197220 | 0.78 | CYP1A2 (0.56) | CYP1A2KMT2AMEN1NPC1TSHR | |
| SCHEMBL11530272 | 0.74 | POLB (0.49) | KMT2ANPC1LMNASMN1; SMN2HTT | |
| SCHEMBL10658137 | 0.73 | KMT2A (0.49) | CYP1A2KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL27196361 | 0.73 | GSK3B (0.51) | CYP1A2KMT2AMEN1NPC1LMNA | |
| SCHEMBL11508571 | 0.72 | GAA (0.45) | CYP1A2KMT2AMEN1TSHRLMNA | |
| SCHEMBL3567261 | 0.72 | P2RX7 (0.45) | CYP1A2KMT2AMEN1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144339-A | TREATMENT OF BILHARZIASIS | RHONE-POULENC INDUSTRIES (FR) | 1979-03-13 | — | — | US | disclosed |
| US-4138487-A | NEMATOCIDES | RHONE-POULENC INDUSTRIES (FR) | 1979-02-06 | — | — | US | disclosed |
| US-4110450-A | BILHARZIASIS | RHONE-POULENC INDUSTRIES (FR) | 1978-08-29 | — | — | US | disclosed |