Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PLK1 | P53350 | 5/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712617 | 0.85 | PLK1 (0.54) | PLK1TRPV1CNR2HPGDRARB | |
| SCHEMBL11527888 | 0.83 | PLK1 (0.55) | PLK1TRPV1CNR2HPGDRARB | |
| SCHEMBL28111022 | 0.83 | RARB (0.59) | PLK1TRPV1RARBPLK3 | |
| SCHEMBL9151142 | 0.82 | SIGMAR1 (0.53) | KMT2ATHRATHRBPOLBALDH1A1 | |
| SCHEMBL18050363 | 0.82 | TRPV1 (0.46) | PLK1TRPV1HPGDRARBTHRA | |
| SCHEMBL18050362 | 0.82 | TRPV1 (0.46) | PLK1TRPV1HPGDRARBTHRA | |
| SCHEMBL31483533 | 0.82 | PLK1 (0.54) | PLK1TRPV1CNR2HPGDRARB | |
| SCHEMBL10322210 | 0.82 | PLK1 (0.54) | PLK1TRPV1CNR2HPGDRARB | |
| SCHEMBL4603474 | 0.80 | TRPV1 (0.64) | KMT2APLK1TRPV1CNR2HPGD | |
| SCHEMBL1404028 | 0.80 | RARB (0.67) | KMT2APLK1TRPV1CNR2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145444-A | 4-BUTYL-BENZOPHENONE | KAKEN CHEMICAL CO., LTD. (JP) | 1979-03-20 | — | — | US | disclosed |
| US-4124726-A | 2-FLUORO-4'-ALKYLBENZOPHENONE | KAKEN CHEMICAL CO., LTD. (JP) | 1978-11-07 | — | — | US | disclosed |