Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 5/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | PLK3 | Q9H4B4 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.45 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.45 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.45 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11530894 | 0.95 | PLK1 (0.52) | PLK1RARBNPC1GAARAB9A | |
| SCHEMBL11528615 | 0.91 | GAA (0.59) | PLK1NPC1GAARAB9ATHRB | |
| SCHEMBL11527888 | 0.83 | PLK1 (0.55) | PLK1TRPV1RARBTHRATHRB | |
| SCHEMBL28111022 | 0.83 | RARB (0.59) | PLK1TRPV1RARBPLK3 | |
| SCHEMBL11528595 | 0.82 | KMT2A (0.55) | PLK1TRPV1RARBTHRATHRB | |
| SCHEMBL31483533 | 0.82 | PLK1 (0.54) | PLK1TRPV1RARBNPC1RAB9A | |
| SCHEMBL9712617 | 0.82 | PLK1 (0.54) | PLK1TRPV1RARBTHRATHRB | |
| SCHEMBL1688009 | 0.81 | FAAH (0.52) | PLK1 | |
| SCHEMBL4603474 | 0.80 | TRPV1 (0.64) | PLK1TRPV1RARBNPC1RAB9A | |
| SCHEMBL1404028 | 0.80 | RARB (0.67) | PLK1TRPV1RARBTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014176460-A1 | METHODS OF TREATING BEHAVIORIAL AND/OR MENTAL DISORDERS | CHAU DAVID T (US) | 2014-10-30 | — | — | WO | disclosed |
| US-8486922-B2 | Composition | CHEN CHIEN-HUNG (TW) | 2013-07-16 | — | — | US | disclosed |
| US-20120183600-A1 | NOVEL COMPOSITION FOR TREATING METABOLIC SYNDROME AND OTHER CONDITIONS | CHEN CHIEN-HUNG (US) | 2012-07-19 | — | — | US | disclosed |
| EP-0228996-A2 | Antiflaking agent | WARNER-LAMBERT COMPANY (US) | 1987-07-15 | — | — | EP | disclosed |
| US-4672076-A | Non-steroidal anti-inflammatory compounds and compositions thereof | WARNER-LAMBERT COMPANY (US) | 1987-06-09 | — | — | US | disclosed |
| US-4623663-A | 4-DIMETHYLAMINO BENZOPHENONE | WARNER-LAMBERT COMPANY (US) | 1986-11-18 | — | — | US | disclosed |
| US-4609677-A | 1-PHENYL-1-CYCLOHEXENE AND 4-PHENYLCYCLOHEXANONE | WARNER-LAMBERT COMPANY (US) | 1986-09-02 | — | — | US | disclosed |
| US-4587260-A | Dibenzalacetone and benzylcinnamate as non-steroidal anti-inflammatory compounds and compositions thereof | WARNER-LAMBERT COMPANY (US) | 1986-05-06 | — | — | US | disclosed |
| US-4578405-A | 1-PHENYLCYCLOHEXENE, 4-PHENYLCYCLOHEXANONE | WARNER-LAMBERT COMPANY (US) | 1986-03-25 | — | — | US | disclosed |
| US-4569944-A | Dibenzosuberone as a non-steroidal anti-inflammatory compound and compositions thereof | WARNER-LAMBERT COMPANY (US) | 1986-02-11 | — | — | US | disclosed |
| US-4568697-A | ANTIINFLAMMATORY AGENTS; ANALGESICS/ AGENT, AND ANNEALING | WARNER-LAMBERT COMPANY (US) | 1986-02-04 | — | — | US | disclosed |
| US-4568696-A | DIPHENYL KETONE DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1986-02-04 | — | — | US | disclosed |
| US-4562194-A | BENZOPHENONE COMPOUND IN COMBINATION WITH 3-ISOBUTYL-1-METHYLANTHINE | WARNER-LAMBERT COMPANY (US) | 1985-12-31 | — | — | US | disclosed |
| US-4559328-A | ANALGESICS, ANTISWELLING AGENTS | WARNER-LAMBERT COMPANY (US) | 1985-12-17 | — | — | US | disclosed |
| US-4530844-A | Containing diphenyl ketone compound | WARNER-LAMBERT COMPANY (US) | 1985-07-23 | — | — | US | disclosed |
| US-4145444-A | 4-BUTYL-BENZOPHENONE | KAKEN CHEMICAL CO., LTD. (JP) | 1979-03-20 | — | — | US | disclosed |
| US-4124726-A | 2-FLUORO-4'-ALKYLBENZOPHENONE | KAKEN CHEMICAL CO., LTD. (JP) | 1978-11-07 | — | — | US | disclosed |