Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14518585 | 0.83 | ESR2 (0.46) | MAPTKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11613964 | 0.82 | ESR1 (0.40) | HPGDMAPK1NPSR1NPC1HTT | |
| SCHEMBL574465 | 0.80 | ALDH1A1 (0.53) | HPGDMAPK1NPSR1NPC1HTT | |
| SCHEMBL31545368 | 0.79 | HPGD (0.39) | HPGDMAPK1NPSR1NPC1HTT | |
| SCHEMBL8758914 | 0.79 | ESR1 (0.39) | HPGDMAPK1NPSR1NPC1HTT | |
| SCHEMBL16720974 | 0.78 | HPGD (0.39) | HPGDMAPK1NPSR1NPC1HTT | |
| SCHEMBL30800974 | 0.78 | HPGD (0.39) | HPGDMAPK1NPSR1NPC1HTT | |
| SCHEMBL11315486 | 0.76 | ACHE (0.42) | HPGDMAPK1NPSR1NPC1HTT | |
| SCHEMBL25328955 | 0.75 | IMPDH2 (0.41) | MAPTALDH1A1CYP3A4ESR1ESR2 | |
| SCHEMBL21515894 | 0.74 | ESR1 (0.41) | HPGDMAPK1NPSR1NPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4158027-A | BIPHENOL DERIVATIVES USED AS POLYMERIZATION INHIBITORS | ICI AMERICAS INC. (US) | 1979-06-12 | — | — | US | disclosed |
| US-4112019-A | BISPHENOL POLYMERIZATION INHIBITOR | ICI AMERICAS INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4049731-A | VINYL MONOMERS, BIPHENOL DERIVATIVE AS POLYMERIZATION INHIBITOR | ICI UNITED STATES INC. (US) | 1977-09-20 | — | — | US | disclosed |