Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | BID | P55957 | 3/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.35 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11532650 | 1.00 | PPARA (0.41) | PPARAPPARGPTGS2ALOX5LTB4R | |
| SCHEMBL11531872 | 1.00 | PPARA (0.41) | PPARAPPARGPTGS2ALOX5LTB4R | |
| SCHEMBL2042000 | 0.89 | PPARA (0.43) | PPARAPPARGPTGS2ALOX5LTB4R | |
| SCHEMBL11529563 | 0.89 | PPARA (0.43) | PPARAPPARGPTGS2ALOX5LTB4R | |
| SCHEMBL9169769 | 0.88 | PPARA (0.42) | PPARAPPARGPTGS2ALOX5LTB4R | |
| SCHEMBL8375499 | 0.84 | THRA (0.45) | PPARAPPARGPTGS2ALOX5THRA | |
| SCHEMBL11098797 | 0.84 | PTGS2 (0.38) | PPARAPPARGPTGS2ALOX5LTB4R | |
| SCHEMBL159096 | 0.83 | THRA (0.44) | PPARAPPARGPTGS2ALOX5THRA | |
| SCHEMBL11087732 | 0.83 | THRA (0.44) | PPARAPPARGPTGS2ALOX5THRA | |
| SCHEMBL8011394 | 0.83 | THRA (0.44) | PPARAPPARGPTGS2ALOX5THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136042-A | EXTREME PRESSURE LUBRICANTS | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1979-01-23 | — | — | US | claimed |