Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 9/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | RGS12 | O14924 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533272 | 0.84 | TBXA2R (0.46) | TBXA2RKDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL9472297 | 0.83 | CA2 (0.47) | TBXA2RKDM4EMAPTHPGDHSD17B10 | |
| Methane SCHEMBL11528997 | 0.83 | TBXA2R (0.45) | TBXA2RKDM4EMAPTHPGDHSD17B10 | |
| Methyl Alcohol SCHEMBL11526388 | 0.83 | TBXA2R (0.45) | TBXA2RKDM4EMAPTHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL8879980 | 0.82 | CA2 (0.46) | TBXA2RKDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL11530910 | 0.80 | KDM4E (0.46) | TBXA2RKDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL11529012 | 0.76 | KDM4E (0.42) | TBXA2RKDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL11575568 | 0.76 | SRD5A2 (0.46) | TBXA2RAKR1B1 | |
| Hydrochloric Acid SCHEMBL8880333 | 0.75 | ALDH1A1 (0.47) | TBXA2RKDM4EMAPTHPGDHSD17B10 | |
| Methyl Alcohol SCHEMBL10890406 | 0.75 | KDM4E (0.41) | TBXA2RKDM4EMAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |