Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11525874 | 0.79 | SLC6A4 (0.43) | SLC6A4CHRM2ADRA1ACACNA1FCHRM1 | |
| SCHEMBL2622207 | 0.72 | HRH1 (0.55) | SLC6A4CHRM2ADRA1ACACNA1FCHRM1 | |
| SCHEMBL11524119 | 0.68 | RIPK1 (0.38) | SLC6A4CHRM2ADRA1ACACNA1FCHRM1 | |
| SCHEMBL2910676 | 0.68 | LMNA (0.43) | SLC6A4TSHRCYP2D6MEN1KMT2A | |
| SCHEMBL27168294 | 0.68 | LMNA (0.43) | SLC6A4TSHRCYP2D6MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27765589 | 0.67 | ALDH1A1 (0.42) | SLC6A4CHRM2ADRA1ACACNA1FCHRM1 | |
| SCHEMBL11100775 | 0.66 | MTOR (0.44) | SLC6A4CHRM2ADRA1ACACNA1FCHRM1 | |
| SCHEMBL11526449 | 0.66 | MTOR (0.40) | CHRM2ADRA1ATSHRMTORRAB9A | |
| SCHEMBL5231780 | 0.64 | SLC6A4 (0.43) | SLC6A4CHRM2ADRA1ACACNA1FCHRM1 | |
| SCHEMBL1437981 | 0.63 | MTOR (0.46) | TSHRMTORRAB9AGRM7CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147780-A | α-Amino-phosphonous acids for inhibiting bacteria and yeast | CIBA-GEIGY CORPORATION (US) | 1979-04-03 | — | — | US | disclosed |