Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29405270 | 0.93 | ALOX5 (0.55) | ALDH1A1ALOX15ALOX5PTGS1PTGS2 | |
| SCHEMBL10428376 | 0.79 | MAPT (0.61) | ALDH1A1ALOX15MAPTPOLBLMNA | |
| SCHEMBL9596002 | 0.79 | ALOX5 (0.55) | ALDH1A1ALOX5PTGS1PTGS2POLB | |
| SCHEMBL10449042 | 0.78 | ALOX5 (0.58) | ALDH1A1ALOX15ALOX5PTGS1PTGS2 | |
| Diethylamine SCHEMBL10428507 | 0.77 | MAPT (0.46) | ALDH1A1ALOX5PTGS1PTGS2MAPT | |
| SCHEMBL29738659 | 0.77 | ALOX5 (0.56) | ALDH1A1ALOX15ALOX5PTGS1PTGS2 | |
| SCHEMBL10449258 | 0.77 | ALOX5 (0.56) | ALDH1A1ALOX15ALOX5PTGS1PTGS2 | |
| Hydrochloric Acid SCHEMBL10428505 | 0.76 | MAPT (0.43) | ALDH1A1ALOX5PTGS1PTGS2MAPT | |
| Benzoyl Chloride SCHEMBL11599698 | 0.76 | PTGS2 (0.55) | ALDH1A1ALOX5PTGS1PTGS2LMNA | |
| SCHEMBL29402957 | 0.76 | PTGS2 (0.55) | ALDH1A1ALOX5PTGS1PTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4165383-A | BENZOYL-2,6-DI(T-BUTYL)PHENOL AND DERIVATIVES | RIKER LABORATORIES, INC. (US) | 1979-08-21 | — | — | US | disclosed |