Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | POLA1 | P09884 | 1/20 | 0.35 |
| ▸ | IAPP | P10997 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11529331 | 1.00 | TRPA1 (0.35) | TRPA1POLBPOLA1IAPPPPARG | |
| SCHEMBL11511498 | 0.96 | TRPA1 (0.41) | TRPA1POLBPOLA1PPARGPPARA | |
| SCHEMBL11511502 | 0.96 | TRPA1 (0.41) | TRPA1POLBPOLA1PPARGPPARA | |
| SCHEMBL11526299 | 0.94 | POLB (0.42) | TRPA1POLBPOLA1PPARGPPARA | |
| SCHEMBL11526294 | 0.94 | POLB (0.42) | TRPA1POLBPOLA1PPARGPPARA | |
| SCHEMBL11523888 | 0.94 | POLB (0.42) | TRPA1POLBPOLA1PPARGPPARA | |
| SCHEMBL11523885 | 0.94 | POLB (0.42) | TRPA1POLBPOLA1PPARGPPARA | |
| SCHEMBL11527732 | 0.91 | MAPK1 (0.32) | MAPK1 | |
| SCHEMBL11527735 | 0.91 | MAPK1 (0.32) | MAPK1 | |
| SCHEMBL11761262 | 0.87 | ALDH1A1 (0.35) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161608-A | 11 Hydroxy methyl 11-deoxyprostaglandin E1 | AYERST, MCKENNA AND HARRISON LIMITED (CA) | 1979-07-17 | — | — | US | disclosed |
| US-4100343-A | 11-Deoxyprostaglandin derivatives | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-07-11 | — | — | US | disclosed |
| US-4089898-A | 11-Deoxyprostaglandin derivatives | AYERST, MCKENNA & HARRISON LTD. (CA) | 1978-05-16 | — | — | US | disclosed |
| US-4036856-A | PROSTAGLANDINS | AYERST MCKENNA AND HARRISON LTD. (CA) | 1977-07-19 | — | — | US | disclosed |
| US-4006136-A | Prostaglandin intermediates | AYERST MCKENNA AND HARRISON LTD. (CA) | 1977-02-01 | — | — | US | disclosed |