Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527975 | 0.99 | SMN1; SMN2 (0.39) | SMN1; SMN2NPC1PKMNFKB1RAB9A | |
| Methane SCHEMBL11529085 | 0.86 | ALDH1A1 (0.44) | SMN1; SMN2NPC1RAB9AL3MBTL1MAPT | |
| Methyl Alcohol SCHEMBL11526848 | 0.84 | ALDH1A1 (0.44) | SMN1; SMN2NPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL24650439 | 0.82 | CA1 (0.41) | SMN1; SMN2NPC1PKMNFKB1RAB9A | |
| SCHEMBL11528818 | 0.82 | TBXA2R (0.42) | SMN1; SMN2NPC1PKMNFKB1RAB9A | |
| Methane SCHEMBL10892966 | 0.82 | KDM4E (0.41) | NFKB1MAPTLMNAGAAMEN1 | |
| SCHEMBL11529012 | 0.80 | KDM4E (0.42) | NFKB1MAPTLMNAGAAMEN1 | |
| Methyl Alcohol SCHEMBL10890406 | 0.79 | KDM4E (0.41) | NFKB1MAPTLMNAGAAMEN1 | |
| SCHEMBL8728437 | 0.79 | FFAR1 (0.44) | SMN1; SMN2NPC1PKMNFKB1RAB9A | |
| SCHEMBL8728441 | 0.79 | SMN1; SMN2 (0.39) | SMN1; SMN2NPC1PKMNFKB1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166131-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANTIARTHRITIC AGENT | HEXACHIMIE SOCIETE ANONYME (FR) | 1979-08-28 | — | — | US | disclosed |