Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.40 |
| ▸ | LDHA | P00338 | 2/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LDHB | P07195 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11528818 | 0.88 | TBXA2R (0.42) | CYP4Z1NPC1PKMNFKB1RAB9A | |
| SCHEMBL24650439 | 0.82 | CA1 (0.41) | CYP4Z1NPC1PKMNFKB1RAB9A | |
| SCHEMBL14457829 | 0.82 | FFAR1 (0.42) | FFAR1TBXA2RITGB3ITGA2BDRD3 | |
| SCHEMBL11527975 | 0.80 | SMN1; SMN2 (0.39) | CYP4Z1NPC1PKMNFKB1RAB9A | |
| SCHEMBL8728441 | 0.79 | SMN1; SMN2 (0.39) | CYP4Z1NPC1PKMNFKB1RAB9A | |
| Methane SCHEMBL11529454 | 0.79 | SMN1; SMN2 (0.39) | CYP4Z1NPC1PKMNFKB1RAB9A | |
| SCHEMBL8728448 | 0.78 | TBXA2R (0.71) | PKMTBXA2R | |
| SCHEMBL8730081 | 0.77 | TBXA2R (0.45) | NPC1RAB9ASMN1; SMN2L3MBTL1TBXA2R | |
| SCHEMBL31478141 | 0.77 | LMNA (0.46) | CYP4Z1NPC1PKMNFKB1RAB9A | |
| SCHEMBL6834905 | 0.76 | DRD3 (0.48) | CYP4Z1NPC1PKMNFKB1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750524-A | ADMINISTERING AN SULFAMIDE SUBSTITUTED INDAN DERIVATIVE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0773019-A1 | HYPERLIPEMIA REMEDY | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-14 | — | — | EP | disclosed |
| EP-0589037-B1 | INDIAN DERIVATIVE AND THROMBOXANE ANTAGONIST CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 1996-05-29 | — | — | EP | disclosed |
| US-5409956-A | A sulfonylaminoalkylindan carboxylic acid or ester for treating thrombosis, vasospasm or asthma | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0589037-A1 | INDIAN DERIVATIVE AND THROMBOXANE ANTAGONIST CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-30 | — | — | EP | disclosed |