Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19726331 | 0.83 | AKT1 (0.36) | NPC1RAB9ADRD2DRD3TBXA2R | |
| SCHEMBL24650439 | 0.82 | CA1 (0.41) | SMN1; SMN2NPC1PKMNFKB1RAB9A | |
| SCHEMBL11528818 | 0.82 | TBXA2R (0.42) | SMN1; SMN2NPC1PKMNFKB1RAB9A | |
| SCHEMBL11527975 | 0.80 | SMN1; SMN2 (0.39) | SMN1; SMN2NPC1PKMNFKB1RAB9A | |
| Methane SCHEMBL11529454 | 0.79 | SMN1; SMN2 (0.39) | SMN1; SMN2NPC1PKMNFKB1RAB9A | |
| SCHEMBL8728437 | 0.79 | FFAR1 (0.44) | SMN1; SMN2NPC1PKMNFKB1RAB9A | |
| SCHEMBL31478141 | 0.77 | LMNA (0.46) | SMN1; SMN2NPC1PKMNFKB1RAB9A | |
| SCHEMBL6834905 | 0.76 | DRD3 (0.48) | SMN1; SMN2NPC1PKMNFKB1RAB9A | |
| SCHEMBL9453775 | 0.75 | OPRK1 (0.48) | CYP4F2CYP4A11DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL9368908 | 0.74 | OPRK1 (0.47) | CYP4F2CYP4A11DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750524-A | ADMINISTERING AN SULFAMIDE SUBSTITUTED INDAN DERIVATIVE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |