Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1367246 | 0.89 | KMT2A (0.46) | KMT2AMEN1GAAHTT | |
| SCHEMBL11980194 | 0.80 | BCHE (0.44) | KMT2AMEN1SMN1; SMN2GAAHTT | |
| SCHEMBL9511933 | 0.77 | CNR2 (0.46) | KMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL9047842 | 0.76 | GABRA1 (0.45) | KMT2AMEN1GAACYP2D6 | |
| Cyclopropanecarboxylic Acid Amide SCHEMBL6927157 | 0.72 | SMN1; SMN2 (0.50) | KMT2AMEN1SMN1; SMN2GAAKDM4E | |
| SCHEMBL28418543 | 0.72 | SMN1; SMN2 (0.50) | KMT2AMEN1SMN1; SMN2GAAKDM4E | |
| Cyclopropanecarboxylic Acid Amide SCHEMBL5661 | 0.72 | — | — | |
| SCHEMBL9797557 | 0.72 | SMN1; SMN2 (0.50) | KMT2AMEN1SMN1; SMN2GAAKDM4E | |
| SCHEMBL383436 | 0.72 | SMN1; SMN2 (0.50) | KMT2AMEN1SMN1; SMN2GAAKDM4E | |
| SCHEMBL13332956 | 0.72 | SMN1; SMN2 (0.50) | KMT2AMEN1SMN1; SMN2GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4174455-A | CHAIN EXTENSION, CROSSLINKING AND/OR CURINF OF POLYUREAS, POLYURETHANES, AND EPOXY RESINS | CIBA-GEIGY CORPORATION (US) | 1979-11-13 | — | — | US | disclosed |