Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988669 | 0.85 | CSNK2A1 (0.50) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL9988672 | 0.85 | CSNK2A1 (0.50) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL14360428 | 0.82 | TRPA1 (0.59) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| Thymol SCHEMBL29152602 | 0.81 | LMNA (0.75) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL28238190 | 0.81 | TRPA1 (0.62) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL7458752 | 0.80 | TYR (0.47) | LMNANPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL9988674 | 0.80 | TYR (0.47) | LMNANPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL9294948 | 0.79 | TRPA1 (0.55) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| Thymol SCHEMBL28080455 | 0.79 | TRPA1 (0.78) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL7395695 | 0.78 | LMNA (0.41) | LMNACHRM1ADRA1AHTR2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163759-A | Process for preparing aromatic hydroxyaldehydes | HAARMANN & REIMER GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-08-07 | — | — | US | disclosed |