Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 5/20 | 0.45 |
| ▸ | SLC2A4 | P14672 | 2/20 | 0.45 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24041797 | 0.89 | MAOB (0.52) | BCHESLC2A1CHRM2CHRM1CHRM3 | |
| SCHEMBL24041827 | 0.89 | MAOA (0.46) | BCHEKCNH2MAOBSIGMAR1 | |
| SCHEMBL24041813 | 0.88 | BCHE (0.55) | BCHEABCB1MAOBTDP1 | |
| SCHEMBL24041894 | 0.82 | CYP4F2 (0.54) | BCHESLC2A1SLC2A4SLC2A8CHRM2 | |
| SCHEMBL22964298 | 0.82 | KDM4E (0.55) | BCHESLC2A1SLC2A4SLC2A8CHRM2 | |
| SCHEMBL24041786 | 0.80 | SLC2A1 (0.48) | BCHESLC2A1SLC2A4SLC2A8CHRM2 | |
| SCHEMBL24041762 | 0.79 | BCHE (0.50) | BCHESLC2A1SLC2A4SLC2A8KCNH2 | |
| SCHEMBL24041834 | 0.76 | ABCB1 (0.54) | BCHEKCNH2ABCB1TDP1L3MBTL1 | |
| SCHEMBL24041798 | 0.75 | CHRNA7 (0.50) | KCNH2 | |
| SCHEMBL4949653 | 0.75 | TAAR1 (0.67) | CHRM2CHRM1CHRM3ABCB1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3912972-A1 | SOCE INHIBITORS AND THERAPEUTIC USES THEREOF | Centre Hospitalier Régional et Universitaire de Brest (FR) | 2021-11-24 | — | — | EP | disclosed |