Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 2/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906097 | 0.85 | MMP1 (0.32) | PTPN1FDPSMMP1MMP2MMP3 | |
| SCHEMBL6931264 | 0.82 | — | — | |
| SCHEMBL2721087 | 0.79 | PTPN1 (0.44) | PTPN1TSHRMEN1KMT2A | |
| SCHEMBL1564814 | 0.77 | PTPN1 (0.39) | PTPN1TSHRLMNAMEN1KMT2A | |
| SCHEMBL337595 | 0.77 | MMP1 (0.34) | PTPN1FDPSMMP1MMP2MMP3 | |
| SCHEMBL16048 | 0.75 | CYP4F2 (0.40) | LMNAMEN1KMT2A | |
| SCHEMBL9578846 | 0.75 | FDPS (0.32) | FDPS | |
| SCHEMBL18759662 | 0.75 | CYP4F2 (0.40) | LMNAMEN1KMT2A | |
| SCHEMBL19278938 | 0.73 | CYP4F2 (0.39) | LMNAMEN1KMT2A | |
| SCHEMBL97930 | 0.73 | DGAT1 (0.39) | LMNAFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172146-A | Substituted phenyl derivatives | CIBA-GEIGY CORPORATION (US) | 1979-10-23 | — | — | US | disclosed |
| US-4069344-A | INSECTICIDAL SUBSTITUTED PHENYL DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1978-01-17 | — | — | US | disclosed |