Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11528430 | 0.66 | NOTUM (0.39) | MEN1KMT2AL3MBTL1RECQLNOTUM | |
| SCHEMBL11531245 | 0.64 | ALDH1A1 (0.38) | MEN1KMT2ANOTUMSMN1; SMN2NPC1 | |
| SCHEMBL4339852 | 0.63 | PTGS1 (0.43) | MEN1KMT2AL3MBTL1RECQLPTGS1 | |
| SCHEMBL14278603 | 0.63 | RECQL (0.49) | MEN1KMT2AL3MBTL1RECQLNOTUM | |
| SCHEMBL8302897 | 0.62 | NOTUM (0.47) | MEN1KMT2AL3MBTL1NOTUMSMN1; SMN2 | |
| SCHEMBL11568277 | 0.61 | HRH3 (0.50) | MEN1KMT2AL3MBTL1RECQLNOTUM | |
| SCHEMBL3983896 | 0.60 | RECQL (0.46) | MEN1KMT2AL3MBTL1RECQLNOTUM | |
| SCHEMBL11867988 | 0.59 | RECQL (0.46) | RECQLNOTUMPTGS1PTGS2NPC1 | |
| SCHEMBL11826349 | 0.58 | RECQL (0.44) | MEN1KMT2AL3MBTL1RECQLNOTUM | |
| SCHEMBL30236261 | 0.58 | RECQL (0.53) | RECQLALPLSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136184-A | TRANQUILIZERS, ANTICONVULSANTS, MUSCLE RELAXANTS | SANDOZ, INC. (US) | 1979-01-23 | — | — | US | disclosed |
| US-4055644-A | CNS DEPRESSANTS | SANDOZ, INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3931176-A | CNS DEPRESSANT | SANDOZ INC. (US) | 1976-01-06 | — | — | US | disclosed |