Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | RPA1 | P27694 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28462310 | 0.78 | ALDH1A1 (0.52) | MAPTHSP90AA1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11867988 | 0.73 | RECQL (0.46) | RECQLLMNAALDH1A1CYP1A2CYP2A6 | |
| SCHEMBL8664728 | 0.69 | CYP1A2 (0.52) | RECQLLMNASMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL491020 | 0.68 | SMN1; SMN2 (0.45) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL491288 | 0.67 | CYP1A2 (0.40) | RECQLMAPTHTTLMNASMN1; SMN2 | |
| SCHEMBL11223011 | 0.67 | LMNA (0.61) | MAPTLMNAALDH1A1CYP1A2CYP2A6 | |
| SCHEMBL11165087 | 0.66 | CYP1A2 (0.73) | LMNAALDH1A1CYP1A2CYP2A6NPC1 | |
| SCHEMBL28215 | 0.66 | CYP1A2 (0.73) | LMNAALDH1A1CYP1A2CYP2A6NPC1 | |
| SCHEMBL3952742 | 0.66 | CYP1A2 (0.73) | LMNAALDH1A1CYP1A2CYP2A6NPC1 | |
| SCHEMBL8664748 | 0.66 | CYP1A2 (0.48) | RECQLMAPTHTTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111732545-B | 2, 3-dihydrospiro [ imidazole-4, 1 ′ -indene]Compounds and preparation method thereof | 华侨大学 | 2023-03-10 | — | — | CN | disclosed |