Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NSD2 | O96028 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11530500 | 0.83 | MYC (0.41) | ALDH1A1TDP1HSD17B10TSHRKDM4E | |
| SCHEMBL7840819 | 0.80 | MAPT (0.44) | RAPGEF4ALDH1A1TDP1HSD17B10CASP6 | |
| SCHEMBL11530445 | 0.80 | TSHR (0.41) | ALDH1A1TDP1HSD17B10TSHRKDM4E | |
| SCHEMBL7830050 | 0.78 | ALKBH5 (0.45) | RAPGEF4ALDH1A1TDP1HSD17B10CASP6 | |
| SCHEMBL11569662 | 0.77 | TSHR (0.36) | ALDH1A1TDP1HSD17B10TSHRKDM4E | |
| SCHEMBL10703638 | 0.75 | ALDH1A1 (0.36) | RAPGEF4ALDH1A1TDP1HSD17B10CASP6 | |
| SCHEMBL11140976 | 0.75 | KDM4E (0.42) | RAPGEF4ALDH1A1TDP1HSD17B10CASP6 | |
| SCHEMBL9397382 | 0.74 | ALDH1A1 (0.57) | ALDH1A1TDP1HSD17B10CASP6KDM4E | |
| SCHEMBL11528391 | 0.73 | ALDH1A1 (0.37) | ALDH1A1TDP1HSD17B10TSHRCASP6 | |
| SCHEMBL11531529 | 0.72 | KDM4E (0.41) | ALDH1A1TDP1HSD17B10TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141890-A | FIBER-REACTIVE | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |