Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | CASP6 | P55212 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11139711 | 0.93 | KDM4E (0.40) | KDM4EALDH1A1RAPGEF4GAAMAPT | |
| SCHEMBL9397382 | 0.89 | ALDH1A1 (0.57) | KDM4EALDH1A1GAAMAPTPOLB | |
| SCHEMBL7830050 | 0.86 | ALKBH5 (0.45) | KDM4EALDH1A1RAPGEF4GAAMAPT | |
| SCHEMBL7840819 | 0.81 | MAPT (0.44) | KDM4EALDH1A1RAPGEF4GAAMAPT | |
| SCHEMBL8076096 | 0.79 | ALKBH5 (0.45) | KDM4EALDH1A1GAAMAPTPOLB | |
| SCHEMBL10703638 | 0.78 | ALDH1A1 (0.36) | KDM4EALDH1A1RAPGEF4GAAMAPT | |
| SCHEMBL8990040 | 0.77 | ALDH1A1 (0.43) | KDM4EALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL5159217 | 0.75 | ALDH1A1 (0.58) | KDM4EALDH1A1GAAMAPTPOLB | |
| SCHEMBL11530274 | 0.75 | RAPGEF4 (0.36) | KDM4EALDH1A1RAPGEF4GAAMAPT | |
| SCHEMBL5162071 | 0.73 | ALDH1A1 (0.37) | KDM4EALDH1A1GAAMAPTCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4378312-A | CONTAINING 1,3,5-TRIAZINE RING(S); WILL FORM COMPLEX WITH COPPER, COBALT OR CHROMIUM | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-03-29 | — | — | US | disclosed |