Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527258 | 0.88 | MAPT (0.49) | MAPTELANELMNAL3MBTL1KDM4E | |
| SCHEMBL11533785 | 0.88 | MAPT (0.48) | MAPTELANELMNAL3MBTL1KDM4E | |
| SCHEMBL11535223 | 0.77 | ALDH1A1 (0.48) | MAPTELANELMNAL3MBTL1KDM4E | |
| SCHEMBL11537481 | 0.77 | KDM4E (0.53) | MAPTELANELMNAL3MBTL1KDM4E | |
| SCHEMBL11531585 | 0.74 | L3MBTL1 (0.48) | MAPTL3MBTL1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9144209 | 0.73 | KDM4E (0.53) | MAPTLMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL22478566 | 0.72 | ALDH1A1 (0.67) | LMNAKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL11532443 | 0.72 | KDM4E (0.51) | MAPTELANELMNAL3MBTL1KDM4E | |
| SCHEMBL5525935 | 0.71 | ALDH1A1 (0.72) | LMNAKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL5791184 | 0.71 | ALDH1A1 (0.42) | MAPTELANEKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137313-A | ANTICOAGULANTS, ANTIPHLOGISTIC AGENTS | BOEHRINGER INGELHEIM GMBH (DE) | 1979-01-30 | — | — | US | disclosed |