Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11532944 | 0.88 | ALDH1A1 (0.51) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL11530482 | 0.77 | MAPT (0.51) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL11533785 | 0.74 | MAPT (0.48) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL11530508 | 0.73 | KDM4E (0.68) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL22478566 | 0.73 | ALDH1A1 (0.67) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL11526552 | 0.71 | ALDH1A1 (0.54) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL10086142 | 0.70 | ALDH1A1 (0.58) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL2351246 | 0.70 | NOD2 (0.51) | KDM4EALDH1A1HSD17B10HPGDELANE | |
| SCHEMBL30639157 | 0.70 | MAPT (0.49) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL26605167 | 0.70 | MAPT (0.49) | KDM4EALDH1A1HSD17B10HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137313-A | ANTICOAGULANTS, ANTIPHLOGISTIC AGENTS | BOEHRINGER INGELHEIM GMBH (DE) | 1979-01-30 | — | — | US | disclosed |