SCHEMBL9230252

SCHEMBL9230252

C=C(C)C(=O)OCCN1C(C)(C)CCCC1(C)C

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.42
TSHR P16473 4/20 0.41
ALDH1A1 P00352 2/20 0.37
NFKB1 P19838 1/20 0.34
CYP2C19 P33261 1/20 0.34
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11807662 0.88 TSHR (0.39) TSHRNFKB1CYP2C19
SCHEMBL11807659 0.83 TSHR (0.40) TSHRNFKB1CYP2C19
SCHEMBL11811701 0.83 ALDH1A1 (0.39) TSHRALDH1A1NFKB1CYP2C19
SCHEMBL11744218 0.83 THRB (0.41) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL11806697 0.81 TSHR (0.37) TSHRNFKB1CYP2C19
SCHEMBL8849326 0.79 THRB (0.38) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL11541240 0.78 TSHR (0.33) TSHRNFKB1CYP2C19
SCHEMBL11807014 0.78 ADRA2A (0.38) TSHRNFKB1CYP2C19
SCHEMBL11530639 0.78 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL69841 0.77 TSHR (0.47) THRBTSHRALDH1A1NFKB1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120156608-A1 TONER FOR ELECTROSTATIC IMAGE DEVELOPMENT KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2012-06-21 US disclosed
US-5476882-A Containing 2,2,6,6-tetraalkylpiperidine derivative CIBA-GEIGY CORPORATION (US) 1995-12-19 US disclosed
US-5274016-A Crosslinked polyolefin core and stabilizer of a 2,2,6,6-tetramethylpiperidine derivative having at least one ethylenic double bone CIBA-GEIGY CORPORATION (US) 1993-12-28 US disclosed
EP-0296391-B1 LIGHT-STABILIZED POLYMER MICROPARTICLES CONTAINING EPOXY GROUPS CIBA-GEIGY AG (CH) 1993-07-07 EP disclosed
EP-0226538-B1 LIGHT STABILIZED POLYMER MICROPARTICLES Ciba SC Holding AG (CH) 1991-09-11 EP disclosed
US-4894399-A Light-stabilized polymer microparticles containing epoxy groups CIBA-GEIGY CORPORATION (US) 1990-01-16 US disclosed
EP-0296391-A2 Light-stabilized polymer microparticles containing epoxy groups CIBA-GEIGY AG (CH) 1988-12-28 EP disclosed
EP-0114784-B1 ELECTRON-BEAM CURING METHOD FOR COATINGS CIBA-GEIGY AG (CH) 1988-06-01 EP disclosed
EP-0226538-A2 Light stabilized polymer microparticles CIBA-GEIGY AG (CH) 1987-06-24 EP disclosed
US-4511596-A 2,2,6,6-TETRAALKYLPIPERIDINE DERIVATIVES AS CURING PROMOTERS CIBA-GEIGY CORPORATION (US) 1985-04-16 US disclosed
EP-0114784-A2 Electron-beam curing method for coatings CIBA-GEIGY AG (CH) 1984-08-01 EP disclosed
US-4294949-A ACRYLATES OR ACRYLAMIDES WHICH CARRY N-HETEROCYCLIC RINGS CIBA-GEIGY CORPORATION (US) 1981-10-13 US disclosed
US-4276401-A N-Heterocyclic substituted acryloyl polymeric compounds CIBA-GEIGY CORPORATION (US) 1981-06-30 US disclosed
US-4256627-A COMPRISING COMPLEXES OF POLYMERS HAVING UNITS CONTAINING ALKYLPIPERIDINE GROUPS AND NICKEL OR COBALT CARBOXYLATES OR ENOLATES CIBA-GEIGY CORPORATION (US) 1981-03-17 US disclosed
US-4210612-A LIGHT STABILIZERS FOR PLASTICS CIBA-GEIGY CORPORATION (US) 1980-07-01 US disclosed
EP-0010518-A1 Acrylic copolymers bearing N-heterocyclic side rings, their use, and process for their preparation CIBA-GEIGY AG (CH) 1980-04-30 EP disclosed
EP-0001840-A2 Stabilising mixtures, process for stabilising synthetic materials against light with these mixtures and synthetic materials so stabilised CIBA-GEIGY AG (CH) 1979-05-16 EP disclosed
EP-0000496-A1 Acrylic polymers substituted by N-heterocyclic rings and their use as light protection agents CIBA-GEIGY AG (CH) 1979-02-07 EP disclosed