Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 11/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9784323 | 0.86 | NT5E (0.47) | ALDH3A1ALDH1A1LMNASMN1; SMN2ATM | |
| SCHEMBL9817732 | 0.85 | MAPT (0.59) | ALDH3A1ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL10709590 | 0.85 | ALDH3A1 (0.56) | ALDH3A1ALDH1A1LMNASMN1; SMN2ATM | |
| SCHEMBL9784327 | 0.84 | NT5E (0.45) | ALDH3A1ALDH1A1LMNASMN1; SMN2ATM | |
| SCHEMBL10401552 | 0.83 | MAPT (0.47) | ALDH3A1ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL10401890 | 0.82 | MAPT (0.53) | ALDH3A1ALDH1A1LMNAMAPTTDP1 | |
| SCHEMBL130972 | 0.77 | CA2 (0.53) | ALDH1A1LMNATDP1POLBHTT | |
| SCHEMBL10884267 | 0.76 | ALDH3A1 (0.59) | ALDH3A1ALDH1A1LMNASMN1; SMN2ATM | |
| SCHEMBL10401386 | 0.76 | PRMT1 (0.47) | ALDH3A1ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL10531279 | 0.74 | MAPT (0.53) | ALDH3A1ALDH1A1LMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145342-A | NITRO-DIPHENYLAMINO-AZO-PHENYL DYESTUFFS CONTAINING A POLYALKYENEOXY GROUP | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-20 | — | — | US | disclosed |