Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817732 | 0.85 | MAPT (0.59) | MAPTPOLBTDP1EPAS1L3MBTL1 | |
| SCHEMBL11530736 | 0.83 | ALDH3A1 (0.51) | MAPTPOLBTDP1EPAS1L3MBTL1 | |
| SCHEMBL9496798 | 0.82 | CA2 (0.51) | MAPTPOLBTDP1CA2PKM | |
| SCHEMBL10401890 | 0.82 | MAPT (0.53) | MAPTPOLBTDP1EPAS1PKM | |
| SCHEMBL9784323 | 0.82 | NT5E (0.47) | MAPTPOLBTDP1EPAS1PKM | |
| SCHEMBL9784327 | 0.82 | NT5E (0.45) | MAPTPOLBTDP1EPAS1CA2 | |
| SCHEMBL9877924 | 0.80 | PKM (0.64) | MAPTPOLBTDP1PKMKMT2A | |
| SCHEMBL9878208 | 0.80 | PKM (0.54) | MAPTPOLBTDP1PKMKMT2A | |
| SCHEMBL10603322 | 0.78 | CA2 (0.65) | POLBTDP1CA2PKMGAA | |
| SCHEMBL9574410 | 0.75 | CA2 (0.49) | MAPTPOLBCA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4948919-A | DYE INTERMEDIATES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-14 | — | — | US | disclosed |