Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4865510 | 0.82 | KMT2A (0.46) | MEN1KMT2ACYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL18073966 | 0.80 | L3MBTL1 (0.51) | HCAR2MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL501752 | 0.78 | HCAR2 (0.52) | HCAR2NPC1CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL10658137 | 0.78 | KMT2A (0.49) | MEN1KMT2ACYP1A2CYP2C9HIF1A | |
| SCHEMBL27770142 | 0.77 | CA12 (0.50) | HCAR2NPC1CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL8019028 | 0.76 | HCAR2 (0.57) | HCAR2PIK3CDCYP1A2GAATBXA2R | |
| SCHEMBL11529854 | 0.76 | CYP2C9 (0.42) | HCAR2ACACBMEN1KMT2ANPC1 | |
| SCHEMBL5866532 | 0.75 | KMT2A (0.57) | MEN1KMT2ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28119887 | 0.75 | LMNA (0.47) | MEN1KMT2AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL27929947 | 0.73 | HCAR2 (0.46) | HCAR2MEN1KMT2ACYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144339-A | TREATMENT OF BILHARZIASIS | RHONE-POULENC INDUSTRIES (FR) | 1979-03-13 | — | — | US | disclosed |
| US-4138487-A | NEMATOCIDES | RHONE-POULENC INDUSTRIES (FR) | 1979-02-06 | — | — | US | disclosed |
| US-4110450-A | BILHARZIASIS | RHONE-POULENC INDUSTRIES (FR) | 1978-08-29 | — | — | US | disclosed |