Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TERT | O14746 | 10/20 | 0.51 |
| ▸ | PTPRC | P08575 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4291944 | 0.73 | MAOA (0.89) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL4298269 | 0.73 | PTPRC (0.83) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL4299908 | 0.72 | ALDH1A1 (0.90) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL13661737 | 0.71 | MEN1 (0.62) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL22321720 | 0.70 | MAOA (0.83) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL2812760 | 0.69 | MAOA (1.00) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL9175494 | 0.69 | ALDH1A1 (1.00) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL4297885 | 0.69 | TERT (0.78) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL13663715 | 0.69 | PTPRC (0.74) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL9261554 | 0.68 | MAOA (0.97) | MEN1NPC1ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141992-A | Cycloalkylcarboxyamidines and halobenzamidines as anti-amebic agents | AMERICAN CYANAMID COMPANY (US) | 1979-02-27 | — | — | US | disclosed |