Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | CASP3 | P42574 | 2/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.53 |
| ▸ | CDK4 | P11802 | 1/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.53 |
| ▸ | CCND1 | P24385 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11656533 | 0.86 | RAB9A (0.62) | MAPTKDM4ERAB9ANPC1MEN1 | |
| SCHEMBL11411064 | 0.85 | CDK4 (0.67) | MAPTKDM4ERAB9ANPC1MEN1 | |
| SCHEMBL10796083 | 0.83 | RAB9A (0.67) | MAPTKDM4ERAB9ANPC1MEN1 | |
| SCHEMBL30770801 | 0.83 | RAB9A (0.67) | MAPTKDM4ERAB9ANPC1MEN1 | |
| SCHEMBL11652913 | 0.82 | KDM4E (0.61) | MAPTKDM4ERAB9ANPC1MEN1 | |
| SCHEMBL17422798 | 0.79 | RAB9A (0.61) | MAPTKDM4ERAB9ANPC1MEN1 | |
| SCHEMBL11661055 | 0.79 | KDM4E (0.76) | MAPTKDM4ERAB9ANPC1MEN1 | |
| SCHEMBL10460032 | 0.79 | RAB9A (0.59) | MAPTKDM4ERAB9ANPC1MEN1 | |
| SCHEMBL11659391 | 0.77 | KDM4E (0.63) | MAPTKDM4ERAB9ANPC1MEN1 | |
| SCHEMBL2441479 | 0.77 | RIPK1 (0.76) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134909-A | THERMOPLASTIC RESIN STABILIZERS | LABAZ (FR) | 1979-01-16 | — | — | US | disclosed |
| US-4129572-A | TO STABILIZE POLYMERS USED IN FOOD PACKAGING INDUSTRY | LABAZ (FR) | 1978-12-12 | — | — | US | disclosed |