Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP2 | Q9UGN5 | 6/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.53 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.53 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.53 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.53 |
| ▸ | TNKS | O95271 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.53 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.53 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.53 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.53 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.53 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11536264 | 0.83 | PARP10 (0.73) | PARP2PARP10PARP15TNKS2PARP14 | |
| SCHEMBL11744096 | 0.76 | PARP2 (0.46) | PARP2PARP10PARP15TNKS2PARP14 | |
| SCHEMBL11536976 | 0.76 | CHEK1 (0.66) | PARP2PARP10PARP15TNKS2PARP14 | |
| Hydrochloric Acid SCHEMBL11747896 | 0.75 | CHEK1 (0.64) | PARP2PARP10PARP15TNKS2PARP14 | |
| SCHEMBL11534080 | 0.73 | PARP2 (0.55) | PARP2PARP10PARP15TNKS2PARP14 | |
| Acetic Acid SCHEMBL11746162 | 0.70 | CHEK1 (0.57) | POLBNPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL25323961 | 0.69 | PARP10 (1.00) | PARP2PARP10PARP15TNKS2PARP14 | |
| SCHEMBL16441930 | 0.69 | RAB9A (0.48) | PARP2PARP15TNKS2CYP1A1POLB | |
| SCHEMBL11533095 | 0.69 | PARP10 (0.57) | PARP2PARP10PARP15TNKS2PARP14 | |
| SCHEMBL25325088 | 0.69 | PARP2 (1.00) | PARP2PARP10PARP15TNKS2PARP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3937713-A | Process for the preparation of s-triazolo[3,4-b]benzothiazoles | ELI LILLY AND COMPANY (US) | 1976-02-10 | — | — | US | claimed |
| US-4134914-A | 1-Acyl-4-substituted phenyl thiosemicarbazides | ELI LILLY AND COMPANY (US) | 1979-01-16 | — | — | US | disclosed |
| US-4082762-A | 4-(2-HALOPHENYL)-1,2,4-TRIAZOLE-3-THIOL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1978-04-04 | — | — | US | disclosed |
| US-3937713-A | Process for the preparation of s-triazolo[3,4-b]benzothiazoles | ELI LILLY AND COMPANY (US) | 1976-02-10 | — | — | US | disclosed |