Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11536244 | 0.77 | — | — | |
| SCHEMBL20514241 | 0.70 | APLNR (0.54) | — | |
| SCHEMBL11391926 | 0.68 | KMT2A (0.49) | LMNATSHRHTTALDH1A1L3MBTL1 | |
| SCHEMBL11535781 | 0.62 | DCTPP1 (0.39) | LMNATSHRMAPK1HTTSMN1; SMN2 | |
| SCHEMBL1662632 | 0.61 | NQO2 (0.41) | ALDH1A1L3MBTL1 | |
| SCHEMBL29532976 | 0.61 | NQO2 (0.41) | ALDH1A1L3MBTL1 | |
| SCHEMBL26497730 | 0.61 | NQO2 (0.36) | SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL13401052 | 0.60 | TLR8 (0.36) | LMNAMAPK1 | |
| SCHEMBL13548279 | 0.59 | HMGCR (0.48) | — | |
| SCHEMBL16425171 | 0.59 | NQO2 (0.41) | SMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134914-A | 1-Acyl-4-substituted phenyl thiosemicarbazides | ELI LILLY AND COMPANY (US) | 1979-01-16 | — | — | US | disclosed |
| US-4082762-A | 4-(2-HALOPHENYL)-1,2,4-TRIAZOLE-3-THIOL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1978-04-04 | — | — | US | disclosed |
| US-3937713-A | Process for the preparation of s-triazolo[3,4-b]benzothiazoles | ELI LILLY AND COMPANY (US) | 1976-02-10 | — | — | US | disclosed |