Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 6/20 | 0.48 |
| ▸ | DRD4 | P21917 | 4/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.44 |
| ▸ | DRD1 | P21728 | 3/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11531571 | 0.86 | CHRM1 (0.52) | KMT2AMEN1MAPK1MAPTKDM4E | |
| SCHEMBL8234788 | 0.82 | CHRM1 (0.69) | KMT2AMEN1MAPK1MAPTKDM4E | |
| SCHEMBL11533130 | 0.82 | MEN1 (0.52) | KMT2AMEN1MAPK1MAPTKDM4E | |
| SCHEMBL11629466 | 0.82 | DRD2 (0.55) | KMT2AMEN1MAPK1MAPTPOLB | |
| SCHEMBL11531378 | 0.80 | DRD2 (0.74) | KMT2AMEN1MAPK1MAPTPOLB | |
| SCHEMBL5477914 | 0.78 | DRD2 (0.67) | KMT2AMEN1MAPK1MAPTKDM4E | |
| SCHEMBL11631861 | 0.78 | DRD2 (0.55) | KMT2AMEN1MAPK1MAPTPOLB | |
| SCHEMBL11635638 | 0.78 | HRH4 (0.62) | KMT2AMEN1MAPK1MAPTPOLB | |
| SCHEMBL11635201 | 0.78 | DRD2 (0.54) | KMT2AMEN1MAPK1MAPTKDM4E | |
| SCHEMBL11535575 | 0.77 | DRD2 (0.60) | KMT2AMEN1MAPK1KDM4EDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172831-A | CENTRAL NERVOUS SYSTEM | LILLY INDUSTRIES LIMITED (GB) | 1979-10-30 | — | — | US | disclosed |
| US-4115568-A | CNS ACTIVITY | LILLY INDUSTRIES LIMITED (GB) | 1978-09-19 | — | — | US | disclosed |