Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | NOS2 | P35228 | 6/20 | 0.36 |
| ▸ | NOS3 | P29474 | 5/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL817973 | 0.76 | ACHE (0.46) | KMT2ANOS2NOS3ACHE | |
| SCHEMBL19129357 | 0.72 | KMT2A (0.41) | KMT2ANOS2NOS3 | |
| SCHEMBL28523909 | 0.72 | KMT2A (0.41) | KMT2ANOS2NOS3 | |
| SCHEMBL11536198 | 0.71 | KMT2A (0.42) | KMT2ANOS2NOS3ACHEHTR1A | |
| SCHEMBL16161295 | 0.69 | KMT2A (0.41) | KMT2ADRD2DRD3NOS2NOS3 | |
| SCHEMBL28240969 | 0.69 | — | — | |
| SCHEMBL866816 | 0.67 | METAP1 (0.67) | DRD2DRD3ACHEHTR1AHTR2C | |
| SCHEMBL2773408 | 0.67 | — | — | |
| SCHEMBL350515 | 0.66 | — | — | |
| SCHEMBL8057623 | 0.65 | NOS2 (0.56) | KMT2ADRD2DRD3NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156000-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | HEXACHIMIE (FR) | 1979-05-22 | — | — | US | disclosed |
| US-4122091-A | ANALGESIC, ANTIINFLAMMATORY | HEXACHIMIE (FR) | 1978-10-24 | — | — | US | disclosed |