SCHEMBL11533552

SCHEMBL11533552

CCCCN(C(=O)C(CC)CC)c1nc(C)co1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.35
MLYCD O95822 2/20 0.32
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11529811 0.88 ELANE (0.34) ELANEMLYCD
Isamoxole SCHEMBL637131 0.88 MLYCD (0.42) ELANEMLYCDMEN1KMT2A
SCHEMBL11539009 0.86 ELANE (0.35) ELANEMLYCDMEN1KMT2A
SCHEMBL11531284 0.86 ELANE (0.35) ELANEMLYCDMEN1KMT2A
SCHEMBL11536386 0.86 ALDH1A1 (0.31)
SCHEMBL11534704 0.84 MLYCD (0.39) ELANEMLYCD
SCHEMBL11535507 0.83 ELANE (0.49) ELANEMLYCDMEN1KMT2A
SCHEMBL11531011 0.83 MLYCD (0.38) MLYCD
SCHEMBL11537091 0.82 ELANE (0.37) ELANE
SCHEMBL11528434 0.81 ELANE (0.36) ELANEMLYCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4150143-A N-Substituted-acylamino-oxazoles as antiasthma agents LILLY INDUSTRIES LIMITED (GB) 1979-04-17 US disclosed
US-4143047-A 2-SULFINYL AND 2-SULFONYL OXAZOLES LILLY INDUSTRIES LIMITED (GB) 1979-03-06 US disclosed
US-4122183-A ANTIASTHMATIC LILLY INDUSTRIES LIMITED (GB) 1978-10-24 US disclosed