Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11532706 | 0.93 | LMNA (0.49) | LMNAMAPTALDH1A1HSP90AA1MEN1 | |
| SCHEMBL11533163 | 0.92 | TSHR (0.42) | LMNAMAPTALDH1A1HPGDHSP90AA1 | |
| SCHEMBL11533025 | 0.88 | CYP19A1 (0.46) | LMNAMAPTHSP90AA1KMT2ACYP19A1 | |
| SCHEMBL11536312 | 0.88 | TSHR (0.44) | LMNAMAPTALDH1A1HSP90AA1MEN1 | |
| SCHEMBL11530465 | 0.88 | ALDH1A1 (0.42) | LMNAMAPTALDH1A1HPGDHSP90AA1 | |
| SCHEMBL11535387 | 0.86 | LMNA (0.44) | LMNAMAPTALDH1A1HPGDHSP90AA1 | |
| SCHEMBL11533863 | 0.85 | LMNA (0.40) | LMNAMAPTALDH1A1HSP90AA1MEN1 | |
| SCHEMBL11533530 | 0.85 | MAPT (0.46) | LMNAMAPTALDH1A1HSP90AA1MEN1 | |
| SCHEMBL11538658 | 0.85 | CYP19A1 (0.45) | LMNAMAPTALDH1A1HPGDHSP90AA1 | |
| SCHEMBL11531949 | 0.82 | SMN1; SMN2 (0.43) | LMNAMAPTALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140782-A | Combating fungi and nematodes with diphenyl-triazolyl-methanes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |