Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 2/20 | 0.33 |
| ▸ | EDNRA | P25101 | 2/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11532706 | 0.89 | LMNA (0.49) | LMNAHSP90AA1CYP19A1MAPTMEN1 | |
| SCHEMBL11533669 | 0.85 | LMNA (0.43) | LMNAHSP90AA1CYP19A1MAPTMEN1 | |
| SCHEMBL11533025 | 0.84 | CYP19A1 (0.46) | LMNAKIF11HSP90AA1CYP19A1MAPT | |
| SCHEMBL11536312 | 0.84 | TSHR (0.44) | LMNAHSP90AA1CYP19A1MAPTMEN1 | |
| SCHEMBL11533530 | 0.82 | MAPT (0.46) | LMNAKIF11HSP90AA1CYP19A1MAPT | |
| SCHEMBL11538658 | 0.82 | CYP19A1 (0.45) | LMNAHSP90AA1CYP19A1MAPTMEN1 | |
| SCHEMBL11533163 | 0.81 | TSHR (0.42) | LMNAHSP90AA1MAPTMEN1KMT2A | |
| SCHEMBL11536149 | 0.80 | CYP19A1 (0.55) | LMNAKIF11HSP90AA1CYP19A1MAPT | |
| SCHEMBL11533466 | 0.79 | MAPT (0.40) | LMNAMAPTPOLBMEN1KMT2A | |
| SCHEMBL11536409 | 0.78 | LMNA (0.41) | LMNAHSP90AA1CYP19A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140782-A | Combating fungi and nematodes with diphenyl-triazolyl-methanes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |