SCHEMBL11533950

SCHEMBL11533950

c1ccc(-c2cc(-c3ccccc3)[n+](-c3ccccc3)c(-c3ccccc3)c2)cc1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 10/20 0.84
RAB9A P51151 9/20 0.84
NTSR1 P30989 3/20 0.84
HTT P42858 3/20 0.84
MAPK1 P28482 2/20 0.84
NPSR1 Q6W5P4 2/20 0.84
KDM4E B2RXH2 2/20 0.84
UHRF1 Q96T88 1/20 0.84
NR2F2 P24468 1/20 0.65
RAD52 P43351 1/20 0.65
RCE1 Q9Y256 1/20 0.65
KMT2A Q03164 3/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
MEN1 O00255 2/20 0.59
MAPT P10636 2/20 0.59
LMNA P02545 1/20 0.59
NPY1R P25929 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
CA2 P00918 3/20 0.57
CRHBP P24387 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL805082 0.95 NPC1 (0.77) NPC1RAB9ANTSR1HTTMAPK1
SCHEMBL1501554 0.94 NPC1 (0.75) NPC1RAB9ANTSR1HTTMAPK1
Perchlorate SCHEMBL11536227 0.92 NPC1 (1.00) NPC1RAB9ANTSR1HTTMAPK1
SCHEMBL28969696 0.88 NPC1 (0.73) NPC1RAB9ANTSR1HTTMAPK1
SCHEMBL11537385 0.88 NPC1 (0.73) NPC1RAB9ANTSR1HTTMAPK1
SCHEMBL17971504 0.86 NPC1 (0.65) NPC1RAB9ANTSR1HTTMAPK1
Water SCHEMBL29507345 0.86 NPC1 (0.70) NPC1RAB9ANTSR1HTTMAPK1
SCHEMBL17971498 0.86 NPC1 (0.65) NPC1RAB9ANTSR1HTTMAPK1
SCHEMBL4250857 0.86 RAB9A (0.87) NPC1RAB9ANTSR1HTTMAPK1
SCHEMBL17971507 0.85 NPC1 (0.64) NPC1RAB9ANTSR1HTTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7928155-B2 Compositions and methods for polymer composites SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-04-19 US disclosed
US-7915332-B2 Compositions and methods for polymer composites SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-03-29 US disclosed
US-7915332-B2 Compositions and methods for polymer composites SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-03-29 US disclosed
US-20080021175-A1 COMPOSITIONS AND METHODS FOR POLYMER COMPOSITES CITIBANK, N.A., AS COLLATERAL AGENT 2008-01-24 US disclosed
US-20080021175-A1 COMPOSITIONS AND METHODS FOR POLYMER COMPOSITES CITIBANK, N.A., AS COLLATERAL AGENT 2008-01-24 US disclosed
US-20080015330-A1 COMPOSITIONS AND METHODS FOR POLYMER COMPOSITES CITIBANK, N.A., AS COLLATERAL AGENT 2008-01-17 US disclosed
US-20080015330-A1 COMPOSITIONS AND METHODS FOR POLYMER COMPOSITES CITIBANK, N.A., AS COLLATERAL AGENT 2008-01-17 US disclosed
US-20070299187-A1 COMPOSITIONS AND METHODS FOR POLYMER COMPOSITES CITIBANK, N.A., AS COLLATERAL AGENT 2007-12-27 US disclosed
US-20070299187-A1 COMPOSITIONS AND METHODS FOR POLYMER COMPOSITES CITIBANK, N.A., AS COLLATERAL AGENT 2007-12-27 US disclosed
US-20070299186-A1 COMPOSITIONS AND METHODS FOR POLYMER COMPOSITES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2007-12-27 US disclosed
US-20070299186-A1 COMPOSITIONS AND METHODS FOR POLYMER COMPOSITES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2007-12-27 US disclosed
US-20070299189-A1 COMPOSITIONS AND METHODS FOR POLYMER COMPOSITES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2007-12-27 US disclosed
US-20070299189-A1 COMPOSITIONS AND METHODS FOR POLYMER COMPOSITES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2007-12-27 US disclosed
US-20070299188-A1 COMPOSITIONS AND METHODS FOR POLYMER COMPOSITES CITIBANK, N.A., AS COLLATERAL AGENT 2007-12-27 US disclosed
US-20070299188-A1 COMPOSITIONS AND METHODS FOR POLYMER COMPOSITES CITIBANK, N.A., AS COLLATERAL AGENT 2007-12-27 US disclosed
US-4150233-A Water-soluble tetraphenylpyridinium salt for use as an analytical reagents CHADWICK THOMAS C 1979-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080021175-A1 COMPOSITIONS AND METHODS FOR POLYMER COMPOSITES OR10J3, ZYX, PRDX6 NPC1 4721/4885RAB9A 1541/4885NTSR1 4054/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.