Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.77 |
| ▸ | RAB9A | P51151 | 9/20 | 0.77 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.77 |
| ▸ | HTT | P42858 | 3/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.77 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.77 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.70 |
| ▸ | RAD52 | P43351 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | NPY1R | P25929 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 4/20 | 0.62 |
| ▸ | CRHBP | P24387 | 1/20 | 0.62 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533950 | 0.95 | NPC1 (0.84) | NPC1RAB9ANTSR1HTTMAPK1 | |
| Water SCHEMBL29507345 | 0.90 | NPC1 (0.70) | NPC1RAB9ANTSR1HTTMAPK1 | |
| SCHEMBL17971498 | 0.90 | NPC1 (0.65) | NPC1RAB9ANTSR1HTTMAPK1 | |
| SCHEMBL4250857 | 0.90 | RAB9A (0.87) | NPC1RAB9ANTSR1HTTMAPK1 | |
| SCHEMBL17971504 | 0.90 | NPC1 (0.65) | NPC1RAB9ANTSR1HTTMAPK1 | |
| SCHEMBL1501554 | 0.89 | NPC1 (0.75) | NPC1RAB9ANTSR1HTTMAPK1 | |
| Water SCHEMBL1713389 | 0.88 | RAB9A (0.84) | NPC1RAB9ANTSR1HTTMAPK1 | |
| Perchlorate SCHEMBL11536227 | 0.87 | NPC1 (1.00) | NPC1RAB9ANTSR1HTTMAPK1 | |
| SCHEMBL12731966 | 0.87 | NPC1 (0.65) | NPC1RAB9ANTSR1HTTMAPK1 | |
| SCHEMBL19678411 | 0.85 | NPC1 (0.88) | NPC1RAB9ANTSR1HTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120069418-A1 | ELECTROCHROMIC FORMULATION, METHOD FOR THE PRODUCTION THEREOF, AND ORGANIC ELECTROCHROMIC COMPONENT | SIEMENS AKTIENGESELLSCHAFT (DE) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120069418-A1 | ELECTROCHROMIC FORMULATION, METHOD FOR THE PRODUCTION THEREOF, AND ORGANIC ELECTROCHROMIC COMPONENT | HCN2, EPX, HCN4 | NPC1 4367/4885RAB9A 2138/4885NTSR1 4739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.