Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 10/20 | 0.70 |
| ▸ | RAB9A | P51151 | 9/20 | 0.70 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.70 |
| ▸ | HTT | P42858 | 3/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.70 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.65 |
| ▸ | RAD52 | P43351 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | NPY1R | P25929 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 4/20 | 0.58 |
| ▸ | CRHBP | P24387 | 1/20 | 0.58 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL805082 | 0.90 | NPC1 (0.77) | NPC1RAB9ANTSR1HTTMAPK1 | |
| SCHEMBL11533950 | 0.86 | NPC1 (0.84) | NPC1RAB9ANTSR1HTTMAPK1 | |
| SCHEMBL17971498 | 0.85 | NPC1 (0.65) | NPC1RAB9ANTSR1HTTMAPK1 | |
| SCHEMBL17971504 | 0.85 | NPC1 (0.65) | NPC1RAB9ANTSR1HTTMAPK1 | |
| Perchlorate SCHEMBL11536227 | 0.82 | NPC1 (1.00) | NPC1RAB9ANTSR1HTTMAPK1 | |
| SCHEMBL4250857 | 0.81 | RAB9A (0.87) | NPC1RAB9ANTSR1HTTMAPK1 | |
| SCHEMBL1501554 | 0.80 | NPC1 (0.75) | NPC1RAB9ANTSR1HTTMAPK1 | |
| Water SCHEMBL1713389 | 0.79 | RAB9A (0.84) | NPC1RAB9ANTSR1HTTMAPK1 | |
| SCHEMBL28969696 | 0.79 | NPC1 (0.73) | NPC1RAB9ANTSR1HTTMAPK1 | |
| SCHEMBL11537385 | 0.79 | NPC1 (0.73) | NPC1RAB9ANTSR1HTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119784047-A | Cotton water demand perception prediction system | 新疆维吾尔自治区环境保护科学研究院 | 2025-04-08 | — | — | CN | claimed |
| WO-2025037423-A1 | APPARATUS AND METHOD FOR GENERATING ECHO TRAILS OF MOVING OBJECTS FOR A SET OF PULSE WIDTHS | FURUNO ELECTRIC CO., LTD. (JP) | 2025-02-20 | — | — | WO | claimed |
| WO-2025022635-A1 | SYSTEM AND METHOD FOR GENERATING ECHO TRAILS OF MOVING OBJECTS FOR A SET OF DISPLAY RANGES | FURUNO ELECTRIC CO., LTD. (JP) | 2025-01-30 | — | — | WO | claimed |
| CN-120202915-B | Variable irrigation decision-making system | WATER RESOURCES RESEARCH INSTITUTE OF SHANDONG PROVINCE (CN) | 2026-05-26 | — | — | CN | disclosed |
| EP-3965738-B1 | METHOD FOR PRODUCTION OF LIPOSOMES | UNIV DO MINHO (PT) | 2025-08-06 | — | — | EP | disclosed |
| CN-120124319-A | Regional weather element prediction error assessment method based on multidimensional deviation | 南京信息工程大学 | 2025-06-10 | — | — | CN | disclosed |
| US-20250162082-A1 | LASER PROCESSING METHOD, LASER PROCESSING APPARATUS, AND ELECTRONIC DEVICE MANUFACTURING METHOD | GIGAPHOTON INC. (JP) | 2025-05-22 | — | — | US | disclosed |
| CN-119784047-A | Cotton water demand perception prediction system | 新疆维吾尔自治区环境保护科学研究院 | 2025-04-08 | — | — | CN | disclosed |
| EP-3686888-B1 | DEVICE AND METHOD FOR QUANTIZING THE GAINS OF THE ADAPTIVE AND FIXED CONTRIBUTIONS OF THE EXCITATION IN A CELP CODEC | VOICEAGE EVS LLC (US) | 2025-04-02 | — | — | EP | disclosed |
| WO-2025037423-A1 | APPARATUS AND METHOD FOR GENERATING ECHO TRAILS OF MOVING OBJECTS FOR A SET OF PULSE WIDTHS | FURUNO ELECTRIC CO., LTD. (JP) | 2025-02-20 | — | — | WO | disclosed |
| WO-2025037423-A1 | APPARATUS AND METHOD FOR GENERATING ECHO TRAILS OF MOVING OBJECTS FOR A SET OF PULSE WIDTHS | FURUNO ELECTRIC CO., LTD. (JP) | 2025-02-20 | — | — | WO | disclosed |
| WO-2024239827-A1 | DIFFUSION MODEL-BASED INFERENCE ACCELERATION METHOD AND SYSTEM FOR TEXT-TO-IMAGE GENERATION TASK | 阿里云计算有限公司 | 2024-11-28 | — | — | WO | disclosed |
| CN-114611814-B | Urban traffic flow prediction method for aggregating multi-scale space-time similarity information | 中南大学 | 2024-06-07 | — | — | CN | disclosed |
| WO-2024034035-A1 | LASER PROCESSING METHOD, LASER PROCESSING DEVICE, AND PRODUCTION METHOD FOR ELECTRONIC DEVICE | ギガフォトン株式会社 | 2024-02-15 | — | — | WO | disclosed |
| US-11863702-B2 | Acoustic echo cancellation using a control parameter | NOKIA TECHNOLOGIES OY (FI) | 2024-01-02 | — | — | US | disclosed |
| US-20230189546-A1 | LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2023-06-15 | — | — | US | disclosed |
| US-20230046637-A1 | Acoustic Echo Cancellation Using a Control Parameter | NOKIA TECHNOLOGIES OY | 2023-02-16 | — | — | US | disclosed |
| US-11416657-B2 | Method for simulating vertically oriented current in a structure | SONNET SOFTWARE, INC. | 2022-08-16 | — | — | US | disclosed |
| CN-114611814-A | Urban traffic flow prediction method for aggregating multi-scale space-time similar information | 中南大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-114238658-A | Link prediction method and device of time sequence knowledge graph and electronic equipment | 杭州峰景科技有限公司 | 2022-03-25 | — | — | CN | disclosed |