Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633499 | 0.73 | EPHX2 (0.42) | LMNAEPHX2ALDH1A1HSD17B10MEN1 | |
| SCHEMBL9357661 | 0.72 | LMNA (0.70) | KDM4ESMN1; SMN2GPR84FFAR1FFAR4 | |
| SCHEMBL12988170 | 0.72 | EPHX2 (0.65) | SMN1; SMN2LMNAEPHX2BCHEACHE | |
| SCHEMBL25836455 | 0.72 | EPHX2 (0.56) | GPR84FFAR1FFAR4LMNAEPHX2 | |
| SCHEMBL9597315 | 0.70 | LMNA (0.73) | KDM4ESMN1; SMN2GPR84FFAR1FFAR4 | |
| SCHEMBL19248817 | 0.69 | GPR84 (0.43) | KDM4ESMN1; SMN2GPR84FFAR1FFAR4 | |
| SCHEMBL27530726 | 0.68 | EPHX2 (0.45) | FFAR1FFAR4EPHX2CES2CES1 | |
| Dodecanol SCHEMBL9777570 | 0.68 | LMNA (0.61) | SMN1; SMN2GPR84FFAR1FFAR4LMNA | |
| SCHEMBL5503882 | 0.68 | EPHX2 (0.49) | GPR84FFAR1FFAR4EPHX2ALDH1A1 | |
| SCHEMBL5503878 | 0.68 | EPHX2 (0.49) | GPR84FFAR1FFAR4EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137305-A | TOBACCO | WILKINSON SWORD LIMITED (GB) | 1979-01-30 | — | — | US | disclosed |
| US-4137304-A | TOPICAL OR ORAL ADMINISTERED TOBACCO PRODUCT | WILKINSON SWORD LIMITED (GB) | 1979-01-30 | — | — | US | disclosed |
| US-4136164-A | FOR USE IN FOODS, TOPICAL PREPARATIONS, AND TOBACCO | WILKINSON SWORD LIMITED (GB) | 1979-01-23 | — | — | US | disclosed |