Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633097 | 0.85 | EPHX2 (0.40) | EPHX2MEN1KMT2AFAAHMAPK1 | |
| SCHEMBL12988170 | 0.74 | EPHX2 (0.65) | EPHX2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL11534347 | 0.73 | KDM4E (0.40) | EPHX2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9633210 | 0.73 | FAAH (0.59) | NAAAMEN1KMT2AFAAHMAPK1 | |
| Dodecanol SCHEMBL9777570 | 0.71 | LMNA (0.61) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL12988807 | 0.70 | EPHX2 (0.80) | EPHX2MEN1KMT2AFAAHCNR1 | |
| SCHEMBL5503882 | 0.70 | EPHX2 (0.49) | EPHX2MEN1KMT2AFAAHALDH1A1 | |
| SCHEMBL18742134 | 0.70 | EPHX2 (0.49) | EPHX2MEN1KMT2AFAAHALDH1A1 | |
| SCHEMBL5503878 | 0.70 | EPHX2 (0.49) | EPHX2MEN1KMT2AFAAHALDH1A1 | |
| SCHEMBL9633491 | 0.70 | PAOX (0.48) | NAAAMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162315-A | Topical administration of diltiazem | THERAPEUTIC PATCH RESEARCH N.V. | 1992-11-10 | — | — | US | disclosed |